I-CORE - Israeli Centers Of Research Excellence I-CORE - Israeli Centers Of Research Excellence I-CORE - Israeli Centers Of Research Excellence Israeli Centers Of Research Excellence

I-CORE Second Wave

Structural Biology of the Cell - Biophysics and medical technology

Structural Biology of the Cell - Biophysics and medical technology

Integrated Structural Cell Biology

 

Participating Researchers and Institutions:

The group selected to establish this I-CORE is a group under the scientific management of Prof. Gideon Schreiber of the Weizmann Institute of Science consisting of researchers from the Weizmann Institute of Science, Tel-Aviv University and the Technion

 

Scientific Director:

  • Prof. Schreiber Gideon, Biological Chemistry, Weizmann Institute of Science

 

Administrative Director: Meyrav Aviv Goren

 

Scientific Management Members:

 

  • Prof. Ciechanover Aaron, Faculty of Medicine, Cancer and Vascular Biology Research Center, Technion
  • Prof. Frydman Lucio, Chemical Physics, Weizmann Institute of Science
  • Prof. Sussman Joel, Structural Biology, Weizmann Institute of Science
  • Prof. Wolfson Haim, School of Computer Science, Tel Aviv University

 

Additional I-CORE Members:

 

  • Prof. Admon Arie, Biology, Technion
  • Prof. Ben-Tal Nir, Biochemistry and Molecular Biology, Tel Aviv University
  • Prof. Fass Deborah, Structural Biology, Weizmann Institute of Science
  • Dr. Fleishman Sarel, Department of Biological Chemistry, Weizmann Institute of Science
  • Prof. Minsky Abraham, Structural Biology, Weizmann Institute of Science
  • Prof. Nelson Nathan, Biochemistry, Tel Aviv University 

 

New Faculty:

2013-14:

  • Dr. Levy Emmanuel, The Weizmann Institute of Science, returned from Montreal University, Canada
  • Dr. Landau Meytal, Technion, returned from UCLA
  • Dr. Diskin Ron, The Weizmann Institute of Science, returned from Caltech

2014-15:

  • Dr. Yoni Haitin, Tel Aviv University, returned from University of Washington, Seattle, WA, USA 
  • Dr. Yifat Merbl, The Weizmann Institute of Science, returned from Harvard Medical School, Boston, USA

2015-2016

  • Prof. Eyal Gottlieb, Technion,  the cancer metabolism unit at Cancer Research UK, Beatson Institute, Glasgow.

 

Research Focus:

 

Even the simplest living cell is built from many millions of molecules, organized into a machinery of remarkable complexity. Key to understanding cell functions in time and space is knowledge of these molecules’ 3-dimensional structures and of their interactions and adaptations to the dynamic environment of the cell. To achieve this understanding demands a multidisciplinary and integrative approach, which examines structures and mechanisms not only in vitro but also within the intact cell. To this end, this I-CORE have assembled a multidisciplinary team of leading scientists to work closely together in developing the required material and methodological infrastructure and to steward the recruitment of the next generation of Israeli structural cell biologists. The I-CORE team is composed of specialists in X-ray crystallography, NMR, Mass Spectrometry, biophysics of complex systems as well as bioinformatics and protein design.
This I-CORE is built on three pillars: i) Technology development; ii) shared infrastructures; iii) multi-dimensional investigation of key biological questions. New infrastructure will include NMR, Mass Spectrometry, X-ray crystallography, electron and light microscopy, sample preparation, and high-performance computing. This I-CORE will work in close collaboration with the Integrated Structural Biology Infrastructure initiative in Europe (Instruct), which provides pan-European access to the most advanced research facilities in integrated structural biology, thus complementing the facilities to be established within the framework of I-CORE itself. The exchange of scientists, students, techniques and expertise within Instruct will provide a unique and fertile environment for the young generation of scientists that this I-CORE will cultivate. To strengthen the field of cellular structural biology within the Israeli academia, as well public awareness of its importance, we plan to hold international meetings on the topic of structural cell biology, and develop and utilize educational tools that will be used for outreach to undergraduates and high-school students.

 

For more information please contact: meyrav.g@weizmann.ac.il

 

For the I-CORE website: http://www.weizmann.ac.il/icore/scb/