I-CORE - Israeli Centers Of Research Excellence I-CORE - Israeli Centers Of Research Excellence I-CORE - Israeli Centers Of Research Excellence Israeli Centers Of Research Excellence

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I-CORE Workshop on Gene Regulation

I-CORE Workshop on Gene Regulation

I-CORE Workshop on Gene Regulation

Dr. Carmit Levy and Prof. Karen Avraham, I-CORE members, co-organized the I-CORE Workshop


The I-CORE on Gene Regulation in Complex Human Disease organized a 1-day workshop. The day opened with a plenary lecture by Prof. Erez Raz from Munster University, Germany, on germ-cell motility and chemokine-guided germ cell migration in the zebrafish. Other speakers were graduate students and principal investigators from I-CORE. Graduate student Didi Amar (Ron Shamir’s group) described gene expression signatures from Parkinson's Disease patients’ blood. The I-CORE Computation Center, established by Prof. Hanah Margalit and new faculty member Dr. Tommy Kaplan at the Hebrew University, was presented, as well as the new Illumina HiSeq2500 and MiSeq equipment purchased at the I-CORE Genome Center at the Sheba Medical Center, by Prof. Gidi Rechavi. MetCORE, the I-CORE Metabolomics Center at Bar Ilan University, was described by Prof. Shulamit Michaeli, which includes a robust system for magnetic bead-based immunoassays, the Bio-Plex MAGPIX system, the Seahorse Bioscience XF24 analyzer that measures glycolytic and respiratory function in cells, and the Behavioral Center. Dr. Tami Geiger reported the latest advances in the I-CORE Proteomics Center, located at Tel Aviv University. New I-CORE faculty member Dr. Tamar Geiger described her collaborations with Prof. Batsheva Kerem on readthrough treatment of cystic fibrosis, with Prof. Karen Avraham on global proteomic profiling of mouse cochlea and comparison to mRNA and microRNA profiles with Prof. Ron Shamir and Dr. Noam Shomron. Dr. Irit Gat-Viks and Prof. Yinon’s collaboration on decoding genetic variation in innate immunity was reported by Dr. Gat-Viks. Prof. Eran Hornstein, from the Weizmann Institute, joined the meeting to tell about the causes and consequences of dysregulated microRNAs in neurodegeneration, in particular ALS. The day ended with Dr. Amit Tzur reporting his work on cell division in the brain, along with the use of zebrafish morpholinos to study function of genes crucial for brain morphogenesis. The Meeting took place at Tel Aviv University on May 12, 2013 with about 75 participants from the Sheba Medical Center, Tel Aviv University, Hadassah Hospital, Bar Ilan University and the Hebrew University of Jerusalem.

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